Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody

Abstract Immune-oncology (IO) drug therapy is effective against various types of cancer. Although several, potential, clinical predictive markers have been identified, none so far have proven reliable. Herein we evaluated changes in serum alanine aminotransferase (ALT), which is upregulated by the a...

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Autores principales: Takeshi Azuma, Takumi Takeuchi, Yukihide Matayoshi, Shin Namiki, Tetsuya Obara, Kazuhiro Imamura, Mikio Takamori
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2a6f8c097636447083d21605efcde241
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