Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody

Abstract Immune-oncology (IO) drug therapy is effective against various types of cancer. Although several, potential, clinical predictive markers have been identified, none so far have proven reliable. Herein we evaluated changes in serum alanine aminotransferase (ALT), which is upregulated by the a...

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Bibliographic Details
Main Authors: Takeshi Azuma, Takumi Takeuchi, Yukihide Matayoshi, Shin Namiki, Tetsuya Obara, Kazuhiro Imamura, Mikio Takamori
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/2a6f8c097636447083d21605efcde241
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