Pan-urologic cancer genomic subtypes that transcend tissue of origin

Urological cancers have disparate tissues and cells of origin but share many molecular features. Here, the authors use multidimensional and comprehensive molecular characterization to classify urological cancers into nine major genomic subtypes, highlighting potential therapeutic targets.

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Detalles Bibliográficos
Autores principales: Fengju Chen, Yiqun Zhang, Dominick Bossé, Aly-Khan A. Lalani, A. Ari Hakimi, James J. Hsieh, Toni K. Choueiri, Don L. Gibbons, Michael Ittmann, Chad J. Creighton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2a8db6a9c87c4e43a1566658a963a777
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Sumario:Urological cancers have disparate tissues and cells of origin but share many molecular features. Here, the authors use multidimensional and comprehensive molecular characterization to classify urological cancers into nine major genomic subtypes, highlighting potential therapeutic targets.