Pan-urologic cancer genomic subtypes that transcend tissue of origin

Urological cancers have disparate tissues and cells of origin but share many molecular features. Here, the authors use multidimensional and comprehensive molecular characterization to classify urological cancers into nine major genomic subtypes, highlighting potential therapeutic targets.

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Autores principales: Fengju Chen, Yiqun Zhang, Dominick Bossé, Aly-Khan A. Lalani, A. Ari Hakimi, James J. Hsieh, Toni K. Choueiri, Don L. Gibbons, Michael Ittmann, Chad J. Creighton
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2a8db6a9c87c4e43a1566658a963a777
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spelling oai:doaj.org-article:2a8db6a9c87c4e43a1566658a963a7772021-12-02T10:47:59ZPan-urologic cancer genomic subtypes that transcend tissue of origin10.1038/s41467-017-00289-x2041-1723https://doaj.org/article/2a8db6a9c87c4e43a1566658a963a7772017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00289-xhttps://doaj.org/toc/2041-1723Urological cancers have disparate tissues and cells of origin but share many molecular features. Here, the authors use multidimensional and comprehensive molecular characterization to classify urological cancers into nine major genomic subtypes, highlighting potential therapeutic targets.Fengju ChenYiqun ZhangDominick BosséAly-Khan A. LalaniA. Ari HakimiJames J. HsiehToni K. ChoueiriDon L. GibbonsMichael IttmannChad J. CreightonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fengju Chen
Yiqun Zhang
Dominick Bossé
Aly-Khan A. Lalani
A. Ari Hakimi
James J. Hsieh
Toni K. Choueiri
Don L. Gibbons
Michael Ittmann
Chad J. Creighton
Pan-urologic cancer genomic subtypes that transcend tissue of origin
description Urological cancers have disparate tissues and cells of origin but share many molecular features. Here, the authors use multidimensional and comprehensive molecular characterization to classify urological cancers into nine major genomic subtypes, highlighting potential therapeutic targets.
format article
author Fengju Chen
Yiqun Zhang
Dominick Bossé
Aly-Khan A. Lalani
A. Ari Hakimi
James J. Hsieh
Toni K. Choueiri
Don L. Gibbons
Michael Ittmann
Chad J. Creighton
author_facet Fengju Chen
Yiqun Zhang
Dominick Bossé
Aly-Khan A. Lalani
A. Ari Hakimi
James J. Hsieh
Toni K. Choueiri
Don L. Gibbons
Michael Ittmann
Chad J. Creighton
author_sort Fengju Chen
title Pan-urologic cancer genomic subtypes that transcend tissue of origin
title_short Pan-urologic cancer genomic subtypes that transcend tissue of origin
title_full Pan-urologic cancer genomic subtypes that transcend tissue of origin
title_fullStr Pan-urologic cancer genomic subtypes that transcend tissue of origin
title_full_unstemmed Pan-urologic cancer genomic subtypes that transcend tissue of origin
title_sort pan-urologic cancer genomic subtypes that transcend tissue of origin
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/2a8db6a9c87c4e43a1566658a963a777
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