Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis

Abstract Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the various nutrients available during its life cycle. However, in the nutritionally stringent environment of the macrophage phagolysosome, Mtb relies mainly on cholesterol. In previous studies, we demonstrated...

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Autores principales: Jakub Pawełczyk, Anna Brzostek, Alina Minias, Przemysław Płociński, Anna Rumijowska-Galewicz, Dominik Strapagiel, Jolanta Zakrzewska-Czerwińska, Jarosław Dziadek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2aaf6f03abd245e3b8c2e78d904cd3c0
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