The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages.

Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi, little is known about how intracellular R. equi is sensed by macrophages. Here, we discovered that in additi...

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Autores principales: Krystal J Vail, Bibiana Petri da Silveira, Samantha L Bell, Noah D Cohen, Angela I Bordin, Kristin L Patrick, Robert O Watson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/2ac9b5fc418b491eb0a4f4d8c3eba144
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