TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens.

A key feature of many age-related diseases is the oxidative stress-induced accumulation of protein methionine sulfoxide (PMSO) which causes lost protein function and cell death. Proteins whose functions are lost upon PMSO formation can be repaired by the enzyme methionine sulfoxide reductase A (MsrA...

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Auteurs principaux: Lisa A Brennan, Wanda Lee, Marc Kantorow
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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R
Q
Accès en ligne:https://doaj.org/article/2ad02a3a0619478ab10cbeba8c3d912a
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