TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens.
A key feature of many age-related diseases is the oxidative stress-induced accumulation of protein methionine sulfoxide (PMSO) which causes lost protein function and cell death. Proteins whose functions are lost upon PMSO formation can be repaired by the enzyme methionine sulfoxide reductase A (MsrA...
Guardado en:
Autores principales: | Lisa A Brennan, Wanda Lee, Marc Kantorow |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2ad02a3a0619478ab10cbeba8c3d912a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Novel Mechanism for Scavenging of Hypochlorite Involving a Periplasmic Methionine-Rich Peptide and Methionine Sulfoxide Reductase
por: Ryan A. Melnyk, et al.
Publicado: (2015) -
The sRNA RyhB regulates the synthesis of the Escherichia coli methionine sulfoxide reductase MsrB but not MsrA.
por: Julia Bos, et al.
Publicado: (2013) -
Methionine Sulfoxide Reductase A (MsrA) and Its Function in Ubiquitin-Like Protein Modification in <italic toggle="yes">Archaea</italic>
por: Xian Fu, et al.
Publicado: (2017) -
Effect of curcumin on gene expression and protein level of methionine sulfoxide reductase A (MSRA), SOD, CAT and GPx in Freund’s adjuvant inflammation-induced male rats
por: Meshkibaf MH, et al.
Publicado: (2019) -
Methionine sulfoxides on prion protein Helix-3 switch on the alpha-fold destabilization required for conversion.
por: Giorgio Colombo, et al.
Publicado: (2009)