Insulin-Like Growth Factor-1 Differentially Modulates Glutamate-Induced Toxicity and Stress in Cells of the Neurogliovascular Unit

The age-related reduction in circulating levels of insulin-like growth factor-1 (IGF-1) is associated with increased risk of stroke and neurodegenerative diseases in advanced age. Numerous reports highlight behavioral and physiological deficits in blood-brain barrier function and neurovascular commu...

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Auteurs principaux: Cellas A. Hayes, Brandon G. Ashmore, Akshaya Vijayasankar, Jessica P. Marshall, Nicole M. Ashpole
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/2ae0723462b546f8a740f258594c5585
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