A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

Guste Urbonaite and Jimmy Tsz Hang Lee et al. present a droplet-based single-cell sequencing method optimized for use in yeast. They use their method—yeastDropSeq—to investigate the changes in gene expression profiles following treatment with the lifespan-extending compound mycophenolic acid and/or...

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Autores principales: Guste Urbonaite, Jimmy Tsz Hang Lee, Ping Liu, Guillermo E. Parada, Martin Hemberg, Murat Acar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2ae30661d9c24c4f974d766b45d01425
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