A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

Guste Urbonaite and Jimmy Tsz Hang Lee et al. present a droplet-based single-cell sequencing method optimized for use in yeast. They use their method—yeastDropSeq—to investigate the changes in gene expression profiles following treatment with the lifespan-extending compound mycophenolic acid and/or...

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Autores principales:	Guste Urbonaite, Jimmy Tsz Hang Lee, Ping Liu, Guillermo E. Parada, Martin Hemberg, Murat Acar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/2ae30661d9c24c4f974d766b45d01425
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spelling	oai:doaj.org-article:2ae30661d9c24c4f974d766b45d014252021-12-02T16:10:32ZA yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels10.1038/s42003-021-02320-w2399-3642https://doaj.org/article/2ae30661d9c24c4f974d766b45d014252021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02320-whttps://doaj.org/toc/2399-3642Guste Urbonaite and Jimmy Tsz Hang Lee et al. present a droplet-based single-cell sequencing method optimized for use in yeast. They use their method—yeastDropSeq—to investigate the changes in gene expression profiles following treatment with the lifespan-extending compound mycophenolic acid and/or its epistatic agent, guanine.Guste UrbonaiteJimmy Tsz Hang LeePing LiuGuillermo E. ParadaMartin HembergMurat AcarNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Guste Urbonaite Jimmy Tsz Hang Lee Ping Liu Guillermo E. Parada Martin Hemberg Murat Acar A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
description	Guste Urbonaite and Jimmy Tsz Hang Lee et al. present a droplet-based single-cell sequencing method optimized for use in yeast. They use their method—yeastDropSeq—to investigate the changes in gene expression profiles following treatment with the lifespan-extending compound mycophenolic acid and/or its epistatic agent, guanine.
format	article
author	Guste Urbonaite Jimmy Tsz Hang Lee Ping Liu Guillermo E. Parada Martin Hemberg Murat Acar
author_facet	Guste Urbonaite Jimmy Tsz Hang Lee Ping Liu Guillermo E. Parada Martin Hemberg Murat Acar
author_sort	Guste Urbonaite
title	A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
title_short	A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
title_full	A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
title_fullStr	A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
title_full_unstemmed	A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
title_sort	yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mrna levels
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2ae30661d9c24c4f974d766b45d01425
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A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

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