Effects of Aβ-derived peptide fragments on fibrillogenesis of Aβ

Abstract Amyloid β (Aβ) peptide aggregation plays a central role in Alzheimer’s disease (AD) etiology. AD drug candidates have included small molecules or peptides directed towards inhibition of Aβ fibrillogenesis. Although some Aβ-derived peptide fragments suppress Aβ fibril growth, comprehensive a...

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Autores principales: Faisal Abedin, Nabin Kandel, Suren A. Tatulian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2af0e39adc3a49bca758d8f9304b214d
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