Estimation of copy number alterations from exome sequencing data.

Exome sequencing constitutes an important technology for the study of human hereditary diseases and cancer. However, the ability of this approach to identify copy number alterations in primary tumor samples has not been fully addressed. Here we show that somatic copy number alterations can be reliab...

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Bibliographic Details
Main Authors: Rafael Valdés-Mas, Silvia Bea, Diana A Puente, Carlos López-Otín, Xose S Puente
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/2b0816cc8fb04c548861415947af7041
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