Estimation of copy number alterations from exome sequencing data.

Exome sequencing constitutes an important technology for the study of human hereditary diseases and cancer. However, the ability of this approach to identify copy number alterations in primary tumor samples has not been fully addressed. Here we show that somatic copy number alterations can be reliab...

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Autores principales: Rafael Valdés-Mas, Silvia Bea, Diana A Puente, Carlos López-Otín, Xose S Puente
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/2b0816cc8fb04c548861415947af7041
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