Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects

ABSTRACT Type I interferons (IFNs) are key players in the antiviral immune response. Interferon alpha (IFN-α) belongs to this class of IFNs and comprises 12 subtypes that differ from each other in their binding affinities for a common receptor and, thus, in their signaling potencies. Recent data sug...

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Autores principales: Erika Schlaepfer, Audrey Fahrny, Maarja Gruenbach, Stefan P. Kuster, Viviana Simon, Gideon Schreiber, Roberto F. Speck
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/2b0b8de493bf42769700b532a2961a2c
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