Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects
ABSTRACT Type I interferons (IFNs) are key players in the antiviral immune response. Interferon alpha (IFN-α) belongs to this class of IFNs and comprises 12 subtypes that differ from each other in their binding affinities for a common receptor and, thus, in their signaling potencies. Recent data sug...
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Autores principales: | Erika Schlaepfer, Audrey Fahrny, Maarja Gruenbach, Stefan P. Kuster, Viviana Simon, Gideon Schreiber, Roberto F. Speck |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/2b0b8de493bf42769700b532a2961a2c |
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