Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity

Efficient tumor antigen uptake by dendritic cells is facilitated by antibody coating of tumor cells. Here, the authors develop an approach based on hapten vaccination and hapten/tumor targeting ligand conjugates that potentiate anti-tumor immunity by generating and redirecting serum antibodies to tu...

Full description

Saved in:
Bibliographic Details
Main Authors: Brett Schrand, Emily Clark, Agata Levay, Ailem Rabasa Capote, Olivier Martinez, Randall Brenneman, Iris Castro, Eli Gilboa
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/2b3fb79e93c34cee87312bf77ce68f7e
Tags: Add Tag
No Tags, Be the first to tag this record!