Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines

Myosin-10, also known as non-muscle myosin IIB, is a cytoskeletal protein implicated in cardiac development and disease. In humans, it is encoded by the MYH10 gene. Using CRISPR/Cas9 gene editing technology, we generated two MYH10 knockout human iPSC lines – one heterozygous (MRli003-A-1) and one ho...

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Bibliographic Details
Main Authors: Fangfang Zhang, Anna B. Meier, Karl-Ludwig Laugwitz, Tatjana Dorn, Alessandra Moretti
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/2b4c75351f3e433ba604d486cc93cab9
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