Application of hyperbranched rolling circle amplification for direct detection of mycobacterium tuberculosis in clinical sputum specimens.

<h4>Background</h4>Global tuberculosis (TB) control is encumbered by the lack of a rapid and simple detection method for diagnosis, especially in low-resource areas. An isothermal amplification method, hyperbranched rolling circle amplification (HRCA), was optimized to detect Mycobacteri...

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Autores principales: Yang Liu, Yan-Ling Guo, Guang-Lu Jiang, Shi-Jie Zhou, Qi Sun, Xi Chen, Xiu-Jun Chang, Ai-Ying Xing, Feng-Jiao Du, Hong-Yan Jia, Zong-De Zhang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/2b6d92a673d8407a8ec98756343adea1
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