Epstein-Barr Virus Epitope–Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires

ABSTRACT Recognition modes of individual T cell receptors (TCRs) are well studied, but factors driving the selection of TCR repertoires from primary through persistent human virus infections are less well understood. Using deep sequencing, we demonstrate a high degree of diversity of Epstein-Barr vi...

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Détails bibliographiques
Auteurs principaux: Anna Gil, Larisa Kamga, Ramakanth Chirravuri-Venkata, Nuray Aslan, Fransenio Clark, Dario Ghersi, Katherine Luzuriaga, Liisa K. Selin
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
Sujets:
TCR
EBV
Accès en ligne:https://doaj.org/article/2b7944df77564095993254270d153052
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