Antigenic Variation in <italic toggle="yes">Streptococcus pneumoniae</italic> PspC Promotes Immune Escape in the Presence of Variant-Specific Immunity
ABSTRACT Genomic analysis reveals extensive sequence variation and hot spots of recombination in surface proteins of Streptococcus pneumoniae. While this phenomenon is commonly attributed to diversifying selection by host immune responses, there is little mechanistic evidence for the hypothesis that...
Guardado en:
Autores principales: | M. Georgieva, L. Kagedan, Ying-Jie Lu, C. M. Thompson, M. Lipsitch |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2b81aa7c730a496f9fd59a411d7440eb |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Effects of Expression of Streptococcus pneumoniae PspC on the Ability of Streptococcus mitis to Evade Complement-Mediated Immunity
por: Helina Marshall, et al.
Publicado: (2021) -
<italic toggle="yes">Streptococcus pneumoniae</italic> Transmission Is Blocked by Type-Specific Immunity in an Infant Mouse Model
por: Tonia Zangari, et al.
Publicado: (2017) -
<italic toggle="yes">Streptococcus pneumoniae</italic> Modulates <italic toggle="yes">Staphylococcus aureus</italic> Biofilm Dispersion and the Transition from Colonization to Invasive Disease
por: Ryan M. Reddinger, et al.
Publicado: (2018) -
SPD_1495 Contributes to Capsular Polysaccharide Synthesis and Virulence in <italic toggle="yes">Streptococcus pneumoniae</italic>
por: Yun-Dan Zheng, et al.
Publicado: (2020) -
Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A <italic toggle="yes">Streptococcus</italic>
por: Anna Henningham, et al.
Publicado: (2018)