Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene

Abstract The application of Peptide Nucleic Acids (PNAs), mimics of DNA lacking the sugar-phosphate backbone, for antisense/anti-gene therapy and gene editing is limited by their low uptake by cells. Currently, no simple and efficient delivery systems and methods are available to solve this open iss...

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Autores principales: Jessica Gasparello, Alex Manicardi, Alessandro Casnati, Roberto Corradini, Roberto Gambari, Alessia Finotti, Francesco Sansone
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2b8966ee83064b558c0ea0e41dbfe452
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