Cathepsin K knockout protects against cardiac dysfunction in diabetic mice

Abstract Diabetes is a major risk factor for cardiovascular disease and the lysosomal cysteine protease cathepsin K plays a critical role in cardiac pathophysiology. To expand upon our previous findings, we tested the hypothesis that, knockout of cathepsin K protects against diabetes-associated card...

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Bibliographic Details
Main Authors: Rui Guo, Yinan Hua, Olivia Rogers, Travis E. Brown, Jun Ren, Sreejayan Nair
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/2b8fb529c4fd4d61ad3057b47f7187a9
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