Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses

The assembly of the first centrosome occurs upon fertilisation when male centrioles recruit pericentriolar material from the egg cytoplasm. Here the authors identify Wdr8 as a maternally essential protein that is required for centrosome assembly during embryonic mitoses of medaka.

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Autores principales: Daigo Inoue, Manuel Stemmer, Thomas Thumberger, Thomas Ruppert, Felix Bärenz, Joachim Wittbrodt, Oliver J. Gruss
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2ba59a147ad242dbae4f9759a15d0dbe
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