Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types

Cell lines are used ubiquitously in cancer research but how well they represent the tumor type they were derived from is variable. Here, the authors compare transcriptomic profiles of 22 tumor types and cell lines and propose a new comprehensive cell line panel for pan-cancer studies.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: K. Yu, B. Chen, D. Aran, J. Charalel, C. Yau, D. M. Wolf, L. J. van ‘t Veer, A. J. Butte, T. Goldstein, M. Sirota
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/2bd5c7c643b4495ab1808a6fe07e85de
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires