The activated ATM/p53 pathway promotes autophagy in response to oxidative stress-mediated DNA damage induced by Microcystin-LR in male germ cells

Microcystin-LR (MC-LR) is an intracellular toxin with multi-organ toxicity and the testis is one of its important target organs. Although there is increasing research on MC-LR in male reproductive toxicity, the association between DNA damage and autophagy induced by MC-LR in male germ cells are stil...

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Autores principales:	Zhihui Tian, Haohao Liu, Xinghai Chen, Michael D. Losiewicz, Rui Wang, Xingde Du, Bingqian Wang, Ya Ma, Shiyu Zhang, Linjia Shi, Xing Guo, Yongshui Wang, Bingyu Zhang, Shumeng Yuan, Xin Zeng, Huizhen Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Microcystin-LR Reproductive toxicity DNA damage ATM Autophagy Oxidative stress Environmental pollution TD172-193.5 Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/2bde358b27514e6ca45bc28180cfbc4c
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The activated ATM/p53 pathway promotes autophagy in response to oxidative stress-mediated DNA damage induced by Microcystin-LR in male germ cells

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