Uncovering the biosynthetic potential of rare metagenomic DNA using co-occurrence network analysis of targeted sequences

Soil microorganisms are a rich source of bioactive molecules. Here, the authors present a targeted sequencing workflow that reconstructs the clustered organization of biosynthetic domains in metagenomic libraries from amplicon data, thus guiding the discovery of novel metabolites from rare members o...

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Autores principales: Vincent Libis, Niv Antonovsky, Mengyin Zhang, Zhuo Shang, Daniel Montiel, Jeffrey Maniko, Melinda A. Ternei, Paula Y. Calle, Christophe Lemetre, Jeremy G. Owen, Sean F. Brady
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2be2b1b1e1544062afa735e20fcd1c7b
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