Congruent pattern of accessibility identifies minimal pore gate in a non-symmetric voltage-gated sodium channel
Gating of the central pore in voltage-dependent ion channels is mediated by changes in membrane potential. Here, the authors use substituted cysteine accessibility and metal cross-bridging to identify gate residues that form a physical occlusion when closed in a eukaryotic voltage-gated sodium chann...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
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| Subjects: | |
| Online Access: | https://doaj.org/article/2bec79958cb7492980f8567748506534 |
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