External qualification of the Web‐Accessible Population Pharmacokinetic Service–Hemophilia (WAPPS‐Hemo) models for octocog alfa using real patient data

Abstract Background Existing adult patient pharmacokinetic (PK) data from the published Advate vs Kovaltry PK crossover study were used for this validation study. This data set is appropriate for qualification, given that it has not been previously submitted to Web‐Accessible Population Pharmacokine...

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Autores principales: Pierre Chelle, Dagmar Hajducek, Mohammed Mahdi, Stuart Young, Alfonso Iorio, Josh Silvertown, Andrea Edginton
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/2bf0ac22d9094b12aff200d000574de3
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