Interphase human chromosome exhibits out of equilibrium glassy dynamics
The 3D organization of chromosomes within the nuclear space is important for biological functions. Here the authors model chromosomes as self-avoiding copolymers with distinct epigenetic states, and show that the features of experimentally generated contact maps can be reproduced and their dynamics...
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Autores principales: | Guang Shi, Lei Liu, Changbong Hyeon, D. Thirumalai |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/2c075397a936435897898578df34c653 |
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