Interphase human chromosome exhibits out of equilibrium glassy dynamics

The 3D organization of chromosomes within the nuclear space is important for biological functions. Here the authors model chromosomes as self-avoiding copolymers with distinct epigenetic states, and show that the features of experimentally generated contact maps can be reproduced and their dynamics...

Full description

Saved in:
Bibliographic Details
Main Authors: Guang Shi, Lei Liu, Changbong Hyeon, D. Thirumalai
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/2c075397a936435897898578df34c653
Tags: Add Tag
No Tags, Be the first to tag this record!