Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism

Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism

In spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one o...

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Autores principales: Julio César Rodriguez-Gonzalez, Ivones Hernández-Balmaseda, Ken Declerck, Claudina Pérez-Novo, Emilie Logie, Claudia Theys, Patrycja Jakubek, Olga Luisa Quiñones-Maza, Geovanni Dantas-Cassali, Diego Carlos dos Reis, Guy Van Camp, Miriam Teresa Lopes Paz, Idania Rodeiro-Guerra, René Delgado-Hernández, Wim Vanden Berghe
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
Mangiferin (PubChem CID: 5081647)
antitumor
antiangiogenesis
antimetastasic
colon carcinoma
mitochondrial metabolism
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/2c2ad57042394ebf8e1555cab8911302
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https://doaj.org/article/2c2ad57042394ebf8e1555cab8911302

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