Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

Some phages carry genes coding for anti-CRISPR (Acr) proteins that interfere with the activity of bacterial CRISPR-Cas systems. Here, Hynes et al. characterize a new Acr family from streptococcal phages and investigate its potential in genome-editing applications.

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Detalles Bibliográficos
Autores principales: Alexander P. Hynes, Geneviève M. Rousseau, Daniel Agudelo, Adeline Goulet, Beatrice Amigues, Jeremy Loehr, Dennis A. Romero, Christophe Fremaux, Philippe Horvath, Yannick Doyon, Christian Cambillau, Sylvain Moineau
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2c460a63a313487ab66f065d9084faaf
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