Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

Some phages carry genes coding for anti-CRISPR (Acr) proteins that interfere with the activity of bacterial CRISPR-Cas systems. Here, Hynes et al. characterize a new Acr family from streptococcal phages and investigate its potential in genome-editing applications.

Saved in:
Bibliographic Details
Main Authors: Alexander P. Hynes, Geneviève M. Rousseau, Daniel Agudelo, Adeline Goulet, Beatrice Amigues, Jeremy Loehr, Dennis A. Romero, Christophe Fremaux, Philippe Horvath, Yannick Doyon, Christian Cambillau, Sylvain Moineau
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/2c460a63a313487ab66f065d9084faaf
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/2c460a63a313487ab66f065d9084faaf

Similar Items