IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of <named-content content-type="genus-species">Legionella pneumophila</named-content>
ABSTRACT Interferon gamma (IFN-γ) restricts the intracellular replication of many pathogens, but the mechanism by which IFN-γ confers cell-intrinsic pathogen resistance remains unclear. For example, intracellular replication of the bacterial pathogen Legionella pneumophila in macrophages is potently...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2019
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Acceso en línea: | https://doaj.org/article/2c4aa12c2d0e48f185f4175d317f39e4 |
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