IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of <named-content content-type="genus-species">Legionella pneumophila</named-content>

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IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of <named-content content-type="genus-species">Legionella pneumophila</named-content>

ABSTRACT Interferon gamma (IFN-γ) restricts the intracellular replication of many pathogens, but the mechanism by which IFN-γ confers cell-intrinsic pathogen resistance remains unclear. For example, intracellular replication of the bacterial pathogen Legionella pneumophila in macrophages is potently...

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Detalles Bibliográficos
Autores principales:	Jordan V. Price, Daniel Russo, Daisy X. Ji, Roberto A. Chavez, Lucian DiPeso, Angus Yiu-Fai Lee, Jörn Coers, Russell E. Vance
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	Legionella pneumophila host-pathogen interactions innate immunity interferons macrophages Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/2c4aa12c2d0e48f185f4175d317f39e4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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