Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs

Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs

Abstract Inherited retinal dystrophies are an important cause of blindness, for which currently there are no effective treatments. In order to study this heterogeneous group of diseases, adequate disease models are required in order to better understand pathology and to test potential therapies. Ind...

Full description

Saved in:
Bibliographic Details
Main Authors: Conor M. Ramsden, Britta Nommiste, Amelia R. Lane, Amanda-Jayne F. Carr, Michael B. Powner, Matthew J. K. Smart, Li Li Chen, Manickam N. Muthiah, Andrew R. Webster, Anthony T. Moore, Michael E. Cheetham, Lyndon da Cruz, Peter J. Coffey
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/2c6bb3edda1a42e7b46f27b3e51b9e86
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items