Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response

Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response

Mycobacterium tuberculosis (Mtb) bacilli readily aggregate. We previously reported that Mtb aggregates lead to phagocyte death and subsequent efficient replication in the dead infected cells. Here, we examined the transcriptional response of human monocyte derived macrophages to phagocytosis of aggr...

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Autores principales: Hylton E. Rodel, Isabella A. T. M. Ferreira, Carly G. K. Ziegler, Yashica Ganga, Mallory Bernstein, Shi-Hsia Hwa, Kievershen Nargan, Gila Lustig, Gilla Kaplan, Mahdad Noursadeghi, Alex K. Shalek, Adrie J. C. Steyn, Alex Sigal
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
Mycobacterium tuberculosis
TB pathogenesis
aggregation
inflammation
TNF-alpha
phagocytosis
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/2c87105ebf6a454b849cec67673a9715
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https://doaj.org/article/2c87105ebf6a454b849cec67673a9715

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