Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells

The current FDA-approved whole blood stabilization method for circulating tumor cell (CTC) isolation suffers from RNA degradation. Here the authors combine hypothermic preservation and antiplatelet strategies to stabilize whole blood up to 72 h without compromising CTC yield and RNA integrity.

Saved in:
Bibliographic Details
Main Authors: Keith H. K. Wong, Shannon N. Tessier, David T. Miyamoto, Kathleen L. Miller, Lauren D. Bookstaver, Thomas R. Carey, Cleo J. Stannard, Vishal Thapar, Eric C. Tai, Kevin D. Vo, Erin S. Emmons, Haley M. Pleskow, Rebecca D. Sandlin, Lecia V. Sequist, David T. Ting, Daniel A. Haber, Shyamala Maheswaran, Shannon L. Stott, Mehmet Toner
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/2cb65508990f455f91b7d509541cd82f
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/2cb65508990f455f91b7d509541cd82f

Similar Items