Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish

Upstream open reading frames (uORFs) can repress gene expression. Here, Guo-Liang Chew and colleagues use bioinformatics approaches to show that conservation of uORF-mediated translational repression is mediated by sequence features in human, mouse and zebrafish genomes.

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Auteurs principaux: Guo-Liang Chew, Andrea Pauli, Alexander F. Schier
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/2cc05969e6f84064a5e5c7b84f3be8e5
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