Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish

Upstream open reading frames (uORFs) can repress gene expression. Here, Guo-Liang Chew and colleagues use bioinformatics approaches to show that conservation of uORF-mediated translational repression is mediated by sequence features in human, mouse and zebrafish genomes.

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Autores principales:	Guo-Liang Chew, Andrea Pauli, Alexander F. Schier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2cc05969e6f84064a5e5c7b84f3be8e5
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spelling	oai:doaj.org-article:2cc05969e6f84064a5e5c7b84f3be8e52021-12-02T17:32:07ZConservation of uORF repressiveness and sequence features in mouse, human and zebrafish10.1038/ncomms116632041-1723https://doaj.org/article/2cc05969e6f84064a5e5c7b84f3be8e52016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11663https://doaj.org/toc/2041-1723Upstream open reading frames (uORFs) can repress gene expression. Here, Guo-Liang Chew and colleagues use bioinformatics approaches to show that conservation of uORF-mediated translational repression is mediated by sequence features in human, mouse and zebrafish genomes.Guo-Liang ChewAndrea PauliAlexander F. SchierNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Guo-Liang Chew Andrea Pauli Alexander F. Schier Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
description	Upstream open reading frames (uORFs) can repress gene expression. Here, Guo-Liang Chew and colleagues use bioinformatics approaches to show that conservation of uORF-mediated translational repression is mediated by sequence features in human, mouse and zebrafish genomes.
format	article
author	Guo-Liang Chew Andrea Pauli Alexander F. Schier
author_facet	Guo-Liang Chew Andrea Pauli Alexander F. Schier
author_sort	Guo-Liang Chew
title	Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
title_short	Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
title_full	Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
title_fullStr	Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
title_full_unstemmed	Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
title_sort	conservation of uorf repressiveness and sequence features in mouse, human and zebrafish
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2cc05969e6f84064a5e5c7b84f3be8e5
work_keys_str_mv	AT guoliangchew conservationofuorfrepressivenessandsequencefeaturesinmousehumanandzebrafish AT andreapauli conservationofuorfrepressivenessandsequencefeaturesinmousehumanandzebrafish AT alexanderfschier conservationofuorfrepressivenessandsequencefeaturesinmousehumanandzebrafish
_version_	1718380357686919168

Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish

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