Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells

Abstract Ceramide kinase (CERK) phosphorylates ceramide to produce ceramide-1-phosphate (C1P), which is involved in the development of metabolic inflammation. TNF-α modulates inflammatory responses in monocytes associated with various inflammatory disorders; however, the underlying mechanisms remain...

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Auteurs principaux: Fatema Al-Rashed, Zunair Ahmad, Ashley J. Snider, Reeby Thomas, Shihab Kochumon, Motasem Melhem, Sardar Sindhu, Lina M. Obeid, Fahd Al-Mulla, Yusuf A. Hannun, Rasheed Ahmad
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/2cd04aab0a024548a7b6682f41f39173
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