Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe

Abstract Intestinal bacterial β-glucuronidase (βG) hydrolyzes glucuronidated metabolites to their toxic form in intestines, resulting in intestinal damage. The development of a method to inhibit βG is thus important but has been limited by the difficulty of directly assessing enzyme activity in live...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael Chen, Kai-Wen Cheng, Yi-Jou Chen, Chang-Hung Wang, Ta-Chun Cheng, Kuo-Chien Chang, An-Pei Kao, Kuo-Hsiang Chuang
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/2d0f1bd83aa0414da3acd81e41ce2509
Tags: Add Tag
No Tags, Be the first to tag this record!