Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects

Ketamine exerts fast-acting anti-depressant responses. Here the authors show that dopamine D1 receptor expressing neurons in the medial prefrontal cortex contribute to these antidepressant-like effects in mice.

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Autores principales: Brendan D. Hare, Ryota Shinohara, Rong Jian Liu, Santosh Pothula, Ralph J. DiLeone, Ronald S. Duman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2d3337a5795543eab74014329bf3aa23
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