High-performance chemical- and light-inducible recombinases in mammalian cells and mice

High-performance chemical- and light-inducible recombinases in mammalian cells and mice

The availability of high performance recombinases with low basal activity and high dynamic range is limited. Here the authors present a library of over 20 orthogonal split recombinases that can be induced by small molecules, light and temperature in vivo.

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Bibliographic Details
Main Authors: Benjamin H. Weinberg, Jang Hwan Cho, Yash Agarwal, N. T. Hang Pham, Leidy D. Caraballo, Maciej Walkosz, Charina Ortega, Micaela Trexler, Nathan Tague, Billy Law, William K. J. Benman, Justin Letendre, Jacob Beal, Wilson W. Wong
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
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Online Access:https://doaj.org/article/2d4222928cd84b6aa52fbca43ee615fa
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https://doaj.org/article/2d4222928cd84b6aa52fbca43ee615fa

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