Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9
ABSTRACT The genomic DNAs of tailed bacteriophages are commonly modified by the attachment of chemical groups. Some forms of DNA modification are known to protect phage DNA from cleavage by restriction enzymes, but others are of unknown function. Recently, the CRISPR-Cas nuclease complexes were show...
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2015
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| Subjects: | |
| Online Access: | https://doaj.org/article/2d549af73f85431d9cd2431ee86d1e36 |
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