Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis

Traditionally marker-based approaches are used to define haematopoietic cell type or state. Here, the authors use single-cell RNA-seq to establish a cellular hierarchy of lineage development in zebrafish haematopoiesis, and propose a refined model of developmental progression of haematopoietic cells...

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Autores principales: Emmanouil I. Athanasiadis, Jan G. Botthof, Helena Andres, Lauren Ferreira, Pietro Lio, Ana Cvejic
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2d5e464216144b2cb01ae8f3286587fb
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