Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis

Traditionally marker-based approaches are used to define haematopoietic cell type or state. Here, the authors use single-cell RNA-seq to establish a cellular hierarchy of lineage development in zebrafish haematopoiesis, and propose a refined model of developmental progression of haematopoietic cells...

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Autores principales:	Emmanouil I. Athanasiadis, Jan G. Botthof, Helena Andres, Lauren Ferreira, Pietro Lio, Ana Cvejic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2d5e464216144b2cb01ae8f3286587fb
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spelling	oai:doaj.org-article:2d5e464216144b2cb01ae8f3286587fb2021-12-02T14:40:24ZSingle-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis10.1038/s41467-017-02305-62041-1723https://doaj.org/article/2d5e464216144b2cb01ae8f3286587fb2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02305-6https://doaj.org/toc/2041-1723Traditionally marker-based approaches are used to define haematopoietic cell type or state. Here, the authors use single-cell RNA-seq to establish a cellular hierarchy of lineage development in zebrafish haematopoiesis, and propose a refined model of developmental progression of haematopoietic cells.Emmanouil I. AthanasiadisJan G. BotthofHelena AndresLauren FerreiraPietro LioAna CvejicNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emmanouil I. Athanasiadis Jan G. Botthof Helena Andres Lauren Ferreira Pietro Lio Ana Cvejic Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
description	Traditionally marker-based approaches are used to define haematopoietic cell type or state. Here, the authors use single-cell RNA-seq to establish a cellular hierarchy of lineage development in zebrafish haematopoiesis, and propose a refined model of developmental progression of haematopoietic cells.
format	article
author	Emmanouil I. Athanasiadis Jan G. Botthof Helena Andres Lauren Ferreira Pietro Lio Ana Cvejic
author_facet	Emmanouil I. Athanasiadis Jan G. Botthof Helena Andres Lauren Ferreira Pietro Lio Ana Cvejic
author_sort	Emmanouil I. Athanasiadis
title	Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
title_short	Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
title_full	Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
title_fullStr	Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
title_full_unstemmed	Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
title_sort	single-cell rna-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2d5e464216144b2cb01ae8f3286587fb
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Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis

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