A kernelisation approach for multiple d-Hitting Set and its application in optimal multi-drug therapeutic combinations.

Therapies consisting of a combination of agents are an attractive proposition, especially in the context of diseases such as cancer, which can manifest with a variety of tumor types in a single case. However uncovering usable drug combinations is expensive both financially and temporally. By employi...

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Autores principales: Drew Mellor, Elena Prieto, Luke Mathieson, Pablo Moscato
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/2d779693c0f64a8d8317e2ca57508d5e
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