Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration

Abstract Nitroaromatics are among the most important and commonly used chemicals but their production often suffers from multiple unsolved challenges. We have previously described the development of biocatalytic nitration processes driven by an engineered P450 TxtE fusion construct. Herein we report...

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Autores principales: Ran Zuo, Yi Zhang, Chao Jiang, John C. Hackett, Rosemary Loria, Steven D. Bruner, Yousong Ding
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2d7e60a7e8a448e1b0cc0d1e7c0d1adf
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