CXCR3 enables recruitment and site-specific bystander activation of memory CD8+ T cells

T cell bystander activation is induced by systemic inflammation. Here the authors show, using mouse model systems and correlating with human vaccination data, that localized inflammation elicits bystander activation, and that CXCR3 specifically recruits memory CD8+ T cells to sites of activated anti...

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Autores principales: Nicholas J. Maurice, M. Juliana McElrath, Erica Andersen-Nissen, Nicole Frahm, Martin Prlic
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2da069aa679845dc876812190e0373ee
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