An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling

Signalling responses are marked by substantial cell-to-cell variability. Here, the authors propose an information theoretic framework that accounts for multiple inputs and temporal dynamics to analyse how signals flow through shared network components.

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Bibliographic Details
Main Authors: Tomasz Jetka, Karol Nienałtowski, Sarah Filippi, Michael P. H. Stumpf, Michał Komorowski
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/2daf3e307ce74d31936f4ab4d8af4613
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